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Natclovir 250 mg

Buy Natclovir 250 mg (Ganciclovir), Ganciclovir is used in the prevention and treatment of life-threatening or sight-threatening cytomegalovirus (CMV) infections in adults who are immunocompromised (reduced immunity) and in patients with acquired immunodeficiency syndrome (AIDS). It is also used for the treatment of acute herpetic keratitis (inflammation of the cornea of the eye) such as dendrit…

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Description

Natclovir 250 mg (Ganciclovir)

Uses
Ganciclovir is used in the prevention and treatment of life-threatening or sight-threatening cytomegalovirus (CMV) infections in adults who are immunocompromised (reduced immunity) and in patients with acquired immunodeficiency syndrome (AIDS). It is also used for the treatment of acute herpetic keratitis (inflammation of the cornea of the eye) such as dendritic and geographic ulcers. Ganciclovir is also used in patients undergoing transplant for the prevention of CMV retinitis.
How it works
Ganciclovir is an antiviral drug that belongs to a class called synthetic nucleoside analogues. It works by blocking the viral DNA replication a process essential for the virus to grow and multiply. Ganciclovir thus stops the virus from spreading in the body.
What is ganciclovir?

Ganciclovir is an antiviral drug. It slows the growth and spread of the cytomegalovirus. Ganciclovir is used to treat and prevent infections caused by cytomegalovirus. This infection usually occurs in patients who have suppressed immune systems such as patients with AIDS and organ transplant patients. Ganciclovir may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about ganciclovir?

If you are injecting ganciclovir at home, your healthcare provider will give you detailed instructions on how and where to inject the medication. If you do not understand these directions, do not attempt to inject the medication. Contact your healthcare provider for further instructions. Serious side effects affecting the blood have been reported with the use of ganciclovir. Decreased levels of blood cells (white blood cells, red blood cells, and platelets) have occurred. Your doctor may monitor your blood with blood tests. Ganciclovir has caused birth defects in animals, and it is generally not recommended for use during pregnancy. Women should use an effective form of birth control during treatment with ganciclovir. Also, men should use a form of barrier contraception (e.g., condom) during and for at least 90 days following treatment with ganciclovir. Take all of the ganciclovir that has been prescribed, even if you begin to feel better. Your symptoms may start to improve before the infection is completely treated. Take oral ganciclovir with food to increase its absorption by the body.

What should I discuss with my healthcare provider before taking ganciclovir?

Before taking ganciclovir, tell your doctor if you have had an allergic reaction to ganciclovir or acyclovir (Zovirax); kidney disease; or blood problems or low blood counts. You may not be able to take ganciclovir, or you may need a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above. Ganciclovir is in the FDA pregnancy category C. This means that it is not known whether ganciclovir will be harmful to an unborn baby. Ganciclovir has caused birth defects in animals, and it is generally not recommended for use during pregnancy. Women should use an effective form of birth control during treatment with ganciclovir. Also, men should use a form of barrier contraception (e.g., condom) during and for at least 90 days following treatment with ganciclovir. It is not known whether ganciclovir passes into breast milk. Generally, breast-feeding should be avoided during treatment with ganciclovir. Do not take ganciclovir without first talking to your doctor if you are breast-feeding a baby.

How should I take ganciclovir?

Take ganciclovir exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you. Take each oral dose with a full glass of water. Take each oral dose with food to increase the absorption of the drug in your body. Your healthcare provider will administer injectable ganciclovir as an intravenous (into a vein) infusion. If you are injecting ganciclovir at home, your healthcare provider will give you detailed instructions on how and where to inject the medication. If you do not understand these directions, do not attempt to inject the medication. Contact your healthcare provider for further instructions. Do not use any ganciclovir that is discolored, has particles in it, or looks different from your previous doses. Throw away any unused ganciclovir after the amount of tim e determined by your pharmacist or doctor. Take all of the ganciclovir that has been prescribed for you even if you begin to feel better. Your symptoms may start to improve before the infection is completely treated. Your doctor may want you to have blood tests, eye exams, or other evaluations during treatment with ganciclovir to monitor progress and side effects. Store oral ganciclovir at room temperature away from moisture and heat. Dispose of used needles and syringes in a puncture resistant container out of the reach of children. Your healthcare provider will store injectable ganciclovir as directed by the manufacturer or give you detailed storage instructions if you are storing the medication at home.

What happens if I miss a dose?

If a dose of oral ganciclovir is missed, take the missed dose as soon as you remember. If it is almost time for the next dose, skip that dose and take only your next regularly scheduled dose. Do not take a double dose of this medication. Contact your healthcare provider if you miss a dose of injectable ganciclovir.

What happens if I overdose?

Seek emergency medical attention if an overdose is suspected. Symptoms of a ganciclovir overdose include seizures, diarrhea, kidney damage (decreased urine production), liver damage (yellowing of the skin or eyes, abdominal pain), and bone marrow damage (paleness, increased chance of infection, fever and chills).

What should I avoid while taking ganciclovir?

There are no restrictions on food, beverages, or activity during treatment with ganciclovir unless otherwise directed by your doctor.

Expert advice for Natclovir

Ganciclovir should be preferably taken with food.
Ganciclovir is not recommended in children.
Do not drive or operate machinery if you experience visual disturbances due to instillation in eyes, or if you experience convulsion, sedation, dizziness, ataxia and/or confusion.
Your blood cell counts should be monitored while on treatment with ganciclovir especially if you have kidney disorders.
Do not take ganciclovir along with imipenem-cilastatin as it may cause seizures (fits).

Frequently asked ouestions for Natclovir
Q. Is ganciclovir a vesicant/ antibiotic?
No, ganciclovir is not a vesicant/ an antibiotic.
Q. Is ganciclovir a chemotherapy drug?
Yes, ganciclovir is a chemotherapy used for the treatment of viral infections. Do not confuse it with chemotherapy or chemo drugs used for the treatment of cancer.
Q. Is ganciclovir nephrotoxic?
Yes, ganciclovir is known to have nephrotoxicity (toxic to kidneys).
Q. Is ganciclovir a protease inhibitor?
No, ganciclovir is not a protease inhibitor; it belongs to synthetic nucleoside analogues class of antivirals.
Q. Does ganciclovir cover hsv (hepes simplex virus)?
Yes, ganciclovir may be used to treat hsv (hepes simplex virus).
Q. How does ganciclovir cause myelosuppression?
Ganciclovir is directly toxic to colony forming stem cells inside bone marrow which is responsible for RBCs, WBCs and platelets formation, thereby causing myelosuppression.

Additional information

Equivalent Brand

Zirgan

Strength

250 mg

Generic Name

Ganciclovir

Manufacturer

Natco Pharma, India

Pharmaceutical Form

Capsule/s

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